3nw5 | pdb_00003nw5

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Template:STRUCTURE 3nw5

File:3nw5.png

Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11B)

Template:ABSTRACT PUBMED 20675137

About this Structure

3NW5 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Sampognaro AJ, Wittman MD, Carboni JM, Chang C, Greer AF, Hurlburt WW, Sack JS, Vyas DM. Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5027-30. Epub 2010 Jul 15. PMID:20675137 doi:10.1016/j.bmcl.2010.07.045

Page seeded by OCA on Fri Sep 10 13:35:45 2010

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OCA

[1] Sampognaro AJ, Wittman MD, Carboni JM, Chang C, Greer AF, Hurlburt WW, Sack JS, Vyas DM. Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5027-30. Epub 2010 Jul 15. PMID:20675137 doi:10.1016/j.bmcl.2010.07.045

3nw5 | pdb_00003nw5

Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11B)

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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