3kwj | pdb_00003kwj

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Template:STRUCTURE 3kwj

File:3kwj.jpg

Strucutre of human DPP-IV with (2S,3S,11bS)-3-(3-Fluoromethyl-phenyl)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine

Template:ABSTRACT PUBMED 20031408

About this Structure

3KWJ is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Boehringer M, Fischer H, Hennig M, Hunziker D, Huwyler J, Kuhn B, Loeffler BM, Luebbers T, Mattei P, Narquizian R, Sebokova E, Sprecher U, Wessel HP. Aryl- and heteroaryl-substituted aminobenzo[a]quinolizines as dipeptidyl peptidase IV inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1106-8. Epub 2009 Dec 6. PMID:20031408 doi:10.1016/j.bmcl.2009.12.025

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