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AstraZeneca’s Nexium

The following is a list of major phamerceutical compound targets, organized by disease.

Alzheimer’s Disease

Acetylcholinesterase
Amyloid Beta
Gamma-Secratase
Glutamate receptor (GluA2)

Anemia

Erythropoietin

Asthma and other Pulmonary Disease States

Beta-2-Andrenergic Receptor
Leukotriene Receptor

Autoimmune Diseases

Tumor Necrosis Factor Receptor

Blood Clots & Thrombic Events

P2Y12

• • Cancer==
    • Growth Factors
      • Epidermal Growth Factor
        • Epidermal Growth Factor
        • Epidermal Growth Factor Receptor
      • Hepatocyte Growth Factor Receptor
      • Human Epidermal Growth Factor Receptor 2
      • Vascular Growth Factor
        • Vascular Endothelial Growth Factor
        • Vascular Endothelial Growth Factor Receptor
    • Kinases
      • Cell Division Cycle 7-Related Protein Kinase
      • Mitogen-Activated Proteins
        • Mitogen-Activated Protein Kinase
        • Mitogen-Activated Protein Kinase Kinase
        • Mitogen-Activated Protein Kinase Kinase Kinase
          • c-Raf
      • Phosphatidylinositol 3-Kinase
      • Tyrosine Kinase
  • Heat Shock Protein 90
  • p53
  • Mammalian Target of Rapamycin

Compromised Immune System

Granulocyte-macrophage colony-stimulating factor

Diabetes & Hypoglycemia

Peroxisome Proliferator-Activated Receptors

Digestive Diseases

Proton Pump

Erectile Dysfunction

cGMP-Specific Phosphodiesterase Type 5

HIV

Reverse Transcriptase

Hypercholesterolemia (Elevated Cholesterol)

HMG-CoA Reductase

Hypertension & Congestive Heart Failure

Angiotensin-Converting Enzyme
Calcium Channel

Inflammation & Rheumatoid Arthritis

Cyclooxygenase

Schizophrenia, Bipolar Depression, Insomnia, and Anxiety Disorders

Dopamine Receptor
Andrenergic Receptor
Histamine Receptor
Opioid Receptor

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David Canner