3nnz | pdb_00003nnz

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Template:STRUCTURE 3nnz

File:3nnz.jpg

Structure of rat neuronal nitric oxide synthase heme domain complexed with 6-(((3S,4S)-4-(2-(3-Fluorophenethylamino)ethoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine

Template:ABSTRACT PUBMED 20833542

About this Structure

3NNZ is a 2 chains structure with sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  1. Xue F, Li H, Fang J, Roman LJ, Martasek P, Poulos TL, Silverman RB. Peripheral but crucial: A hydrophobic pocket (Tyr706, Leu(337), and Met(336)) for potent and selective inhibition of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2010 Aug 26. PMID:20833542 doi:10.1016/j.bmcl.2010.08.096

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