2pr2 | pdb_00002pr2

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Structure of Mycobacterium tuberculosis enoyl-ACP reductase with bound INH-NADP.

File:2pr2.jpg


2pr2, resolution 2.500Å

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About this Structure

2PR2 is a Single protein structure of sequence from Mycobacterium tuberculosis with DG1 as ligand. Active as [acyl-carrier-protein_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number 1.3.1.9 Full crystallographic information is available from OCA.

Reference

New insight into the mechanism of action of and resistance to isoniazid: interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP., Argyrou A, Vetting MW, Blanchard JS, J Am Chem Soc. 2007 Aug 8;129(31):9582-3. Epub 2007 Jul 18. PMID:17636923 [[Category: Enoyl-[acyl-carrier-protein] reductase (NADH)]]

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