2xs4 | pdb_00002xs4

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Template:STRUCTURE 2xs4

File:2xs4.jpg

STRUCTURE OF KARILYSIN CATALYTIC MMP DOMAIN IN COMPLEX WITH MAGNESIUM

About this Structure

2XS4 is a 2 chains structure with sequences from Tannerella forsythia and Synthetic construct. Full crystallographic information is available from OCA.

Reference

  1. Karim AY, Kulczycka M, Kantyka T, Dubin G, Jabaiah A, Daugherty PS, Thogersen IB, Enghild JJ, Nguyen KA, Potempa J. A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037. Biol Chem. 2010 Jan;391(1):105-17. PMID:19919176 doi:10.1515/BC.2010.009
  2. Koziel J, Karim AY, Przybyszewska K, Ksiazek M, Rapala-Kozik M, Nguyen KA, Potempa J. Proteolytic inactivation of LL-37 by karilysin, a novel virulence mechanism of Tannerella forsythia. J Innate Immun. 2010;2(3):288-93. Epub 2010 Feb 4. PMID:20375548 doi:10.1159/000281881

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