3kxj | pdb_00003kxj

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File:3kxj.jpg

Template:STRUCTURE 3kxj

Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 4,5,6,7-tetrabromo-1-carboxymethylbenzimidazole (K68)

About this Structure

3KXJ is a 1 chain structure with sequence from Zea mays. Full crystallographic information is available from OCA.

Reference

  1. Battistutta R, Mazzorana M, Sarno S, Kazimierczuk Z, Zanotti G, Pinna LA. Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole. Chem Biol. 2005 Nov;12(11):1211-9. PMID:16298300 doi:10.1016/j.chembiol.2005.08.015
  2. Battistutta R, Mazzorana M, Cendron L, Bortolato A, Sarno S, Kazimierczuk Z, Zanotti G, Moro S, Pinna LA. The ATP-binding site of protein kinase CK2 holds a positive electrostatic area and conserved water molecules. Chembiochem. 2007 Oct 15;8(15):1804-9. PMID:17768728 doi:10.1002/cbic.200700307

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