Tol

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Tol is a multiprotein complex consisting of 5 proteins:

Structure

Function

Regulation

It has been shown that the regulation of Tol genes is linked to the cell envelope stability. [1] In studies with E. coli, the tol-pal genes have been induced by RcsC in response to cell envelope stress. RcsC is a transmembrane sensor kinase, and along with the cytoplasmic response regulator RcsB, makes up the RcsBC regulatory system. [1] RcsBC is involved in the regulation of cps genes which code for the biosynthsis machinery of a major componant for the capsula, cholanic acid.

References

  1. ↑ 1.0 1.1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847374/ Cite error: Invalid <ref> tag; name "gene" defined multiple times with different content

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