3ncz | pdb_00003ncz

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Template:STRUCTURE 3ncz

File:3ncz.jpg

X-Ray Co-structure of Rho-Associated Protein Kinase (ROCK1) with a potent 2H-isoquinolin-1-one inhibitor

Template:ABSTRACT PUBMED 20678931

About this Structure

3NCZ is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Ginn JD, Bosanac T, Chen R, Cywin C, Hickey E, Kashem M, Kerr S, Kugler S, Li X, Prokopowicz A 3rd, Schlyer S, Smith JD, Turner MR, Wu F, Young ER. Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 2, optimization for blood pressure reduction in spontaneously hypertensive rats. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5153-6. Epub 2010 Aug 1. PMID:20678931 doi:10.1016/j.bmcl.2010.07.014

Page seeded by OCA on Wed Dec 8 11:50:28 2010

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OCA

[1] Ginn JD, Bosanac T, Chen R, Cywin C, Hickey E, Kashem M, Kerr S, Kugler S, Li X, Prokopowicz A 3rd, Schlyer S, Smith JD, Turner MR, Wu F, Young ER. Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 2, optimization for blood pressure reduction in spontaneously hypertensive rats. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5153-6. Epub 2010 Aug 1. PMID:20678931 doi:10.1016/j.bmcl.2010.07.014

3ncz | pdb_00003ncz

X-Ray Co-structure of Rho-Associated Protein Kinase (ROCK1) with a potent 2H-isoquinolin-1-one inhibitor

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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