3nxx | pdb_00003nxx

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Template:STRUCTURE 3nxx

File:3nxx.jpg

Preferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro-2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase

Template:ABSTRACT PUBMED 21123866

About this Structure

3NXX is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Cody V, Piraino J, Pace J, Li W, Gangjee A. Preferential selection of isomer binding from chiral mixtures: alternate binding modes observed for the E and Z isomers of a series of 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines as ternary complexes with NADPH and human dihydrofolate reductase. Acta Crystallogr D Biol Crystallogr. 2010 Dec;66(Pt 12):1271-7. Epub 2010, Nov 16. PMID:21123866 doi:10.1107/S0907444910035808

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