3oy3 | pdb_00003oy3
From Proteopedia
Crystal structure of ABL T315I mutant kinase domain bound with a DFG-out inhibitor AP24589
Template:ABSTRACT PUBMED 21118377
About this Structure
3OY3 is a 2 chains structure with sequences from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Zhou T, Commodore L, Huang WS, Wang Y, Thomas M, Keats J, Xu Q, Rivera VM, Shakespeare WC, Clackson T, Dalgarno DC, Zhu X. Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance. Chem Biol Drug Des. 2011 Jan;77(1):1-11. doi:, 10.1111/j.1747-0285.2010.01054.x. Epub 2010 Nov 30. PMID:21118377 doi:10.1111/j.1747-0285.2010.01054.x
Page seeded by OCA on Wed Dec 15 08:44:23 2010
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Mus musculus
- Non-specific protein-tyrosine kinase
- Clackson, T.
- Commodore, L.
- Dalgarno, D C.
- Huang, W S.
- Keats, J.
- Rivera, V.
- Shakespeare, W C.
- Thomas, M.
- Wang, Y.
- Xu, Q.
- Zhou, T.
- Zhu, X.
- Atp binding
- Phosphorylation
- Phosphotransferase
- Protein kinase two-domain fold
- Protein-inhibitor complex
- Transferase-transferase inhibitor complex
