3pup | pdb_00003pup

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Template:STRUCTURE 3pup

File:3pup.jpg

Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1)

About this Structure

3PUP is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Maksimoska J, Feng L, Harms K, Yi C, Kissil J, Marmorstein R, Meggers E. Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes. J Am Chem Soc. 2008 Nov 26;130(47):15764-5. PMID:18973295 doi:10.1021/ja805555a
  2. Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3. Chembiochem. 2008 Dec 15;9(18):2933-6. PMID:19035373 doi:10.1002/cbic.200800489

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