2wi4 | pdb_00002wi4
From Proteopedia
ORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONE
About this Structure
2wi4 is a 1 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Brough PA, Barril X, Borgognoni J, Chene P, Davies NG, Davis B, Drysdale MJ, Dymock B, Eccles SA, Garcia-Echeverria C, Fromont C, Hayes A, Hubbard RE, Jordan AM, Jensen MR, Massey A, Merrett A, Padfield A, Parsons R, Radimerski T, Raynaud FI, Robertson A, Roughley SD, Schoepfer J, Simmonite H, Sharp SY, Surgenor A, Valenti M, Walls S, Webb P, Wood M, Workman P, Wright L. Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-d]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone. J Med Chem. 2009 Jul 17. PMID:19610616 doi:10.1021/jm900357y
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Barril, X.
- Borgognoni, J.
- Brough, P A.
- Chene, P.
- Davies, N G.M.
- Davis, B.
- Drysdale, M J.
- Dymock, B.
- Eccles, S A.
- Fromont, C.
- Garcia-Echeverria, C.
- Hayes, A.
- Hubbard, R E.
- Jordan, A M.
- Massey, A.
- Merret, A.
- Padfield, A.
- Parsons, R.
- Radimerski, T.
- Raynaud, F I.
- Robertson, A.
- Roughley, S D.
- Rugaard-Jensen, M.
- Schoepfer, J.
- Simmonite, H.
- Surgenor, A.
- Valenti, M.
- Walls, S.
- Webb, P.
- Wood, M.
- Workman, P.
- Wright, L M.
- Alternative splicing
- Atp-binding
- Atpase
- Chaperone
- Cytoplasm
- Heat shock
- Hsp90
- Nucleotide-binding
- Phosphoprotein
- Phosphorylation
- Pu3
- Stress response
