1j3i | pdb_00001j3i

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Template:STRUCTURE 1j3i

File:1j3i.png

Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with WR99210, NADPH, and dUMP

Template:ABSTRACT PUBMED 12704428

About this Structure

1j3i is a 4 chain structure of Dihydrofolate reductase with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

See Also

Reference

  1. Yuvaniyama J, Chitnumsub P, Kamchonwongpaisan S, Vanichtanankul J, Sirawaraporn W, Taylor P, Walkinshaw MD, Yuthavong Y. Insights into antifolate resistance from malarial DHFR-TS structures. Nat Struct Biol. 2003 May;10(5):357-65. PMID:12704428 doi:10.1038/nsb921

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