1ae8 | pdb_00001ae8

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File:1ae8.png

Template:STRUCTURE 1ae8

HUMAN ALPHA-THROMBIN INHIBITION BY EOC-D-PHE-PRO-AZALYS-ONP

Template:ABSTRACT PUBMED 9217260

About this Structure

1ae8 is a 3 chain structure of Hirudin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. De Simone G, Balliano G, Milla P, Gallina C, Giordano C, Tarricone C, Rizzi M, Bolognesi M, Ascenzi P. Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study. J Mol Biol. 1997 Jun 20;269(4):558-69. PMID:9217260 doi:10.1006/jmbi.1997.1037

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