3c09 | pdb_00003c09

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File:3c09.png

Template:STRUCTURE 3c09

Crystal structure the Fab fragment of matuzumab (Fab72000) in complex with domain III of the extracellular region of EGFR

Template:ABSTRACT PUBMED 18394559

About this Structure

3c09 is a 6 chain structure of Epidermal Growth Factor Receptor and Monoclonal Antibody with sequence from Homo sapiens and Homo sapiens, mus musculus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Schmiedel J, Blaukat A, Li S, Knochel T, Ferguson KM. Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization. Cancer Cell. 2008 Apr;13(4):365-73. PMID:18394559 doi:10.1016/j.ccr.2008.02.019

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OCA

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