2xjx | pdb_00002xjx
From Proteopedia
STRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND
About this Structure
2xjx is a 1 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Woodhead AJ, Angove H, Carr MG, Chessari G, Congreve M, Coyle JE, Cosme J, Graham B, Day PJ, Downham R, Fazal L, Feltell R, Figueroa E, Frederickson M, Lewis J, McMenamin R, Murray CW, O'Brien MA, Parra L, Patel S, Phillips T, Rees DC, Rich S, Smith DM, Trewartha G, Vinkovic M, Williams B, Woolford AJ. Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-di hydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design. J Med Chem. 2010 Jul 28. PMID:20662534 doi:10.1021/jm100060b
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Callaghan, O.
- Carr, M G.
- Chessari, G.
- Congreve, M.
- Cowan, S.
- Coyle, J E.
- Downham, R.
- Figueroa, E.
- Frederickson, M.
- Graham, B.
- Mcmenamin, R.
- Murray, C W.
- Obrien, M A.
- Patel, S.
- Phillips, T R.
- Williams, G.
- Woodhead, A J.
- Woolford, A J.A.
- Atp binding domain
- Chaperone
- Stress response
