1jla | pdb_00001jla

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Template:STRUCTURE 1jla

File:1jla.png

CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH TNK-651

Template:ABSTRACT PUBMED 11575933

About this Structure

1jla is a 2 chain structure of Reverse transcriptase with sequence from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.

See Also

Reference

  1. Ren J, Nichols C, Bird L, Chamberlain P, Weaver K, Short S, Stuart DI, Stammers DK. Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors. J Mol Biol. 2001 Sep 28;312(4):795-805. PMID:11575933 doi:https://dx.doi.org/10.1006/jmbi.2001.4988

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OCA

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