2r2m | pdb_00002r2m
From Proteopedia
2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors
About this Structure
2r2m is a 3 chain structure of Hirudin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T. 2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:17889527 doi:10.1016/j.bmcl.2007.09.013
Proteopedia Page Contributors and Editors (what is this?)
Categories:
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- Hirudo medicinalis
- Homo sapiens
- Thrombin
- Spurlino, J.
- Acute phase
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Kringle
- Polymorphism
- Protease
- Protease inhibitor
- Secreted
- Serine protease
- Serine protease inhibitor
- Sulfation
- Zymogen
