3heg | pdb_00003heg
From Proteopedia
P38 in complex with Sorafenib
About this Structure
3heg is a 1 chain structure of [[]] with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Namboodiri HV, Bukhtiyarova M, Ramcharan J, Karpusas M, Lee Y, Springman EB. Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry. 2010 May 4;49(17):3611-8. PMID:20337484 doi:10.1021/bi100070r
