3pjc | pdb_00003pjc

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Template:STRUCTURE 3pjc

File:3pjc.jpg

Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family

Template:ABSTRACT PUBMED 21155605

About this Structure

3pjc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Thoma G, Nuninger F, Falchetto R, Hermes E, Tavares GA, Vangrevelinghe E, Zerwes HG. Identification of a Potent Janus Kinase 3 Inhibitor with High Selectivity within the Janus Kinase Family. J Med Chem. 2010 Dec 14. PMID:21155605 doi:10.1021/jm101157q

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