2p8s | pdb_00002p8s

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Template:STRUCTURE 2p8s

File:2p8s.png

Human dipeptidyl peptidase IV/CD26 in complex with a cyclohexalamine inhibitor

Template:ABSTRACT PUBMED 17433672

About this Structure

2p8s is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Biftu T, Scapin G, Singh S, Feng D, Becker JW, Eiermann G, He H, Lyons K, Patel S, Petrov A, Sinha-Roy R, Zhang B, Wu J, Zhang X, Doss GA, Thornberry NA, Weber AE. Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3384-7. Epub 2007 Apr 2. PMID:17433672 doi:10.1016/j.bmcl.2007.03.095

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