1rwq | pdb_00001rwq

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Template:STRUCTURE 1rwq

File:1rwq.png

Human Dipeptidyl peptidase IV in complex with 5-aminomethyl-6-(2,4-dichloro-phenyl)-2-(3,5-dimethoxy-phenyl)-pyrimidin-4-ylamine

Template:ABSTRACT PUBMED 15006388

About this Structure

1rwq is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Peters JU, Weber S, Kritter S, Weiss P, Wallier A, Boehringer M, Hennig M, Kuhn B, Loeffler BM. Aminomethylpyrimidines as novel DPP-IV inhibitors: a 10(5)-fold activity increase by optimization of aromatic substituents. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1491-3. PMID:15006388 doi:10.1016/j.bmcl.2004.01.019

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