2qoe | pdb_00002qoe

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Template:STRUCTURE 2qoe

File:2qoe.png

Human Dipeptidyl Peptidase IV in complex with a Triazolopiperazine-based beta amino acid Inhibitor

Template:ABSTRACT PUBMED 17827003

About this Structure

2qoe is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Kowalchick JE, Leiting B, Pryor KD, Marsilio F, Wu JK, He H, Lyons KA, Eiermann GJ, Petrov A, Scapin G, Patel RA, Thornberry NA, Weber AE, Kim D. Design, synthesis, and biological evaluation of triazolopiperazine-based beta-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitors. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5934-9. Epub 2007 Aug 23. PMID:17827003 doi:10.1016/j.bmcl.2007.07.100

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