3n7y | pdb_00003n7y

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File:3n7y.jpg

Template:STRUCTURE 3n7y

Crystal Structure of the Grb2 SH2 Domain in Complex with a 20-Membered Macrocyclic Ligand Having the Sequence pYVNV

Template:ABSTRACT PUBMED 21116482

About this Structure

3n7y is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Delorbe JE, Clements JH, Whiddon BB, Martin SF. Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions. ACS Med Chem Lett. 2010 Nov 11;1(8):448-452. PMID:21116482 doi:10.1021/ml100142y

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OCA

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