2xku | pdb_00002xku

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File:2xku.jpg

Template:STRUCTURE 2xku

PRION-LIKE CONVERSION DURING AMYLOID FORMATION AT ATOMIC RESOLUTION

Template:ABSTRACT PUBMED 21255727

About this Structure

2xku is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  1. Eichner T, Kalverda AP, Thompson GS, Homans SW, Radford SE. Conformational Conversion during Amyloid Formation at Atomic Resolution. Mol Cell. 2011 Jan 21;41(2):161-72. PMID:21255727 doi:10.1016/j.molcel.2010.11.028
  2. Eichner T, Radford SE. A generic mechanism of beta2-microglobulin amyloid assembly at neutral pH involving a specific proline switch. J Mol Biol. 2009 Mar 13;386(5):1312-26. PMID:19452600

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