2qdf | pdb_00002qdf
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Structure of N-terminal domain of E. Coli YaeT
Overview
Integral beta-barrel proteins are found in the outer membranes of, mitochondria, chloroplasts, and Gram-negative bacteria. The machine that, assembles these proteins contains an integral membrane protein, called, YaeT in Escherichia coli, which has one or more polypeptide, transport-associated (POTRA) domains. The crystal structure of a, periplasmic fragment of YaeT reveals the POTRA domain fold and suggests a, model for how POTRA domains can bind different peptide sequences, as, required for a machine that handles numerous beta-barrel protein, precursors. Analysis of POTRA domain deletions shows which are essential, and provides a view of the spatial organization of this assembly machine.
About this Structure
2QDF is a Single protein structure of sequence from Escherichia coli with MG as ligand. Full crystallographic information is available from OCA.
Reference
Structure and function of an essential component of the outer membrane protein assembly machine., Kim S, Malinverni JC, Sliz P, Silhavy TJ, Harrison SC, Kahne D, Science. 2007 Aug 17;317(5840):961-4. PMID:17702946
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