DNase Activity

Many Colicins exhibit enzymatic DNase activity as their cytotoxic activity to kill the targeted E. coli cell. The structure shows the DNase domain of Colicin E9 bound to its Colicin Immunity Protein, Im9.

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2k5x, 1 NMR models (default scene)
Gene:	imm, ceiE9 (Escherichia coli), col, cei (Escherichia coli)
Related:	1imq, 1fsj, 1emv
Structural annotation: Resources: InterPro : Ipr000290, Ipr003058, Ipr016128, Ipr003615 Pfam : PF01320
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

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Gemma McGoldrick, Michal Harel