3q4c | pdb_00003q4c

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Template:STRUCTURE 3q4c

File:3q4c.jpg

Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292

Template:ABSTRACT PUBMED 19371126

About this Structure

3q4c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Xie P, Streu C, Qin J, Bregman H, Pagano N, Meggers E, Marmorstein R. The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. Biochemistry. 2009 Jun 16;48(23):5187-98. PMID:19371126 doi:10.1021/bi802067u

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