3f6u | pdb_00003f6u
From Proteopedia
Crystal structure of human Activated Protein C (APC) complexed with PPACK
About this Structure
3f6u is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Schmidt AE, Padmanabhan K, Underwood MC, Bode W, Mather T, Bajaj SP. Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loops. J Biol Chem. 2002 Aug 9;277(32):28987-95. Epub 2002 May 23. PMID:12029084 doi:10.1074/jbc.M201892200
- Mather T, Oganessyan V, Hof P, Huber R, Foundling S, Esmon C, Bode W. The 2.8 A crystal structure of Gla-domainless activated protein C. EMBO J. 1996 Dec 16;15(24):6822-31. PMID:9003757
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Bajaj, S P.
- Bode, W.
- Mather, T.
- Padmanabhan, K.
- Schmidt, A E.
- Underwood, M C.
- Cleavage on pair of basic residue
- Disease mutation
- Egf-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Plasma calcium binding
- Polymorphism
- Protease
- Re-refinement
- Revised version of the coordinate file pdb 1aut
- Serine protease
- Thrombophilia
- Zymogen
