1qk4 | pdb_00001qk4

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File:1qk4.png

Template:STRUCTURE 1qk4

TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE IMP COMPLEX

Template:ABSTRACT PUBMED 10545170

About this Structure

1qk4 is a 4 chain structure with sequence from Toxoplasma gondii. Full crystallographic information is available from OCA.

Reference

  1. Heroux A, White EL, Ross LJ, Borhani DW. Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex. Biochemistry. 1999 Nov 2;38(44):14485-94. PMID:10545170
  2. Heroux A, White EL, Ross LJ, Davis RL, Borhani DW. Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg(2+) ions bound: insights into the catalytic mechanism. Biochemistry. 1999 Nov 2;38(44):14495-506. PMID:10545171
  3. Vasanthakumar G, van Ginkel S, Parish G. Isolation and sequencing of a cDNA encoding the hypoxanthine-guanine phosphoribosyltransferase from Toxoplasma gondii. Gene. 1994 Sep 15;147(1):153-4. PMID:8088544

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