2qny | pdb_00002qny
From Proteopedia
Crystal structure of the complex between the A246F mutant of mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and SS-(2-hydroxyethyl) O-decyl ester carbono(dithioperoxoic) acid
Template:ABSTRACT PUBMED 18420147
About this Structure
2qny is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Sachdeva S, Musayev FN, Alhamadsheh MM, Scarsdale JN, Wright HT, Reynolds KA. Separate entrance and exit portals for ligand traffic in Mycobacterium tuberculosis FabH. Chem Biol. 2008 Apr;15(4):402-12. PMID:18420147 doi:10.1016/j.chembiol.2008.03.007
- Scarsdale JN, Kazanina G, He X, Reynolds KA, Wright HT. Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III. J Biol Chem. 2001 Jun 8;276(23):20516-22. Epub 2001 Mar 8. PMID:11278743 doi:10.1074/jbc.M010762200
- Musayev F, Sachdeva S, Scarsdale JN, Reynolds KA, Wright HT. Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A. J Mol Biol. 2005 Mar 11;346(5):1313-21. Epub 2005 Jan 20. PMID:15713483 doi:10.1016/j.jmb.2004.12.044
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Beta-ketoacyl-acyl-carrier-protein synthase I
- Mycobacterium tuberculosis
- Alhamadsheh, M.
- Musayev, F.
- Reynolds, K A.
- Sachdeva, S.
- Scarsdale, J N.
- Wright, H T.
- Acyltransferase
- Cytoplasm
- Enzyme inhibitor complex
- Fatty acid biosynthesis
- Lipid synthesis
- Mechanism based inhibitor
- Multifunctional enzyme
- Myobacterium tuberculosis
- Structural basis for substrate specificity
- Transferase
