3h6v | pdb_00003h6v
From Proteopedia
Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5206 at 2.10 A resolution
Template:ABSTRACT PUBMED 19591837
About this Structure
3h6v is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Hald H, Ahring PK, Timmermann DB, Liljefors T, Gajhede M, Kastrup JS. Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2. J Mol Biol. 2009 Sep 4;391(5):906-17. Epub 2009 Jul 8. PMID:19591837 doi:10.1016/j.jmb.2009.07.002
- Armstrong N, Gouaux E. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron. 2000 Oct;28(1):165-81. PMID:11086992
- Sun Y, Olson R, Horning M, Armstrong N, Mayer M, Gouaux E. Mechanism of glutamate receptor desensitization. Nature. 2002 May 16;417(6886):245-53. PMID:12015593 doi:10.1038/417245a
