1ohy | pdb_00001ohy

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Revision as of 19:43, 14 March 2011 by OCA (talk | contribs) (Protected "1ohy" [edit=sysop:move=sysop])
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File:1ohy.png

Template:STRUCTURE 1ohy

4-AMINOBUTYRATE-AMINOTRANSFERASE INACTIVATED BY GAMMA-ETHYNYL GABA

Template:ABSTRACT PUBMED 14534310

About this Structure

1ohy is a 4 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA.

Reference

  1. Storici P, De Biase D, Bossa F, Bruno S, Mozzarelli A, Peneff C, Silverman RB, Schirmer T. Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin. J Biol Chem. 2004 Jan 2;279(1):363-73. Epub 2003 Oct 8. PMID:14534310 doi:10.1074/jbc.M305884200
  2. Storici P, Capitani G, De Biase D, Moser M, John RA, Jansonius JN, Schirmer T. Crystal structure of GABA-aminotransferase, a target for antiepileptic drug therapy. Biochemistry. 1999 Jul 6;38(27):8628-34. PMID:10393538 doi:10.1021/bi990478j

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