1ql7 | pdb_00001ql7

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File:1ql7.png

Template:STRUCTURE 1ql7

FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN

About this Structure

1ql7 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  1. Stubbs MT, Reyda S, Dullweber F, Moller M, Klebe G, Dorsch D, Mederski WW, Wurziger H. pH-dependent binding modes observed in trypsin crystals: lessons for structure-based drug design. Chembiochem. 2002 Mar 1;3(2-3):246-9. PMID:11921406
  2. Renatus M, Bode W, Huber R, Sturzebecher J, Stubbs MT. Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase. J Med Chem. 1998 Dec 31;41(27):5445-56. PMID:9876114 doi:10.1021/jm981068g
  3. Stubbs MT, Huber R, Bode W. Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. FEBS Lett. 1995 Nov 13;375(1-2):103-7. PMID:7498454

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