1un3 | pdb_00001un3

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File:1un3.png

Template:STRUCTURE 1un3

CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT T44D

Template:ABSTRACT PUBMED 14756559

About this Structure

1un3 is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1h0f. Full crystallographic information is available from OCA.

Reference

  1. Holloway DE, Chavali GB, Hares MC, Baker MD, Subbarao GV, Shapiro R, Acharya KR. Crystallographic studies on structural features that determine the enzymatic specificity and potency of human angiogenin: Thr44, Thr80, and residues 38-41. Biochemistry. 2004 Feb 10;43(5):1230-41. PMID:14756559 doi:10.1021/bi035654+
  2. Leonidas DD, Shapiro R, Allen SC, Subbarao GV, Veluraja K, Acharya KR. Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. J Mol Biol. 1999 Jan 22;285(3):1209-33. PMID:9918722 doi:10.1006/jmbi.1998.2378
  3. Curran TP, Shapiro R, Riordan JF. Alteration of the enzymatic specificity of human angiogenin by site-directed mutagenesis. Biochemistry. 1993 Mar 9;32(9):2307-13. PMID:8095159

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