2p0c | pdb_00002p0c
From Proteopedia
Catalytic Domain of the Proto-oncogene Tyrosine-protein Kinase MER
About this Structure
2p0c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Huang X, Finerty P Jr, Walker JR, Butler-Cole C, Vedadi M, Schapira M, Parker SA, Turk BE, Thompson DA, Dhe-Paganon S. Structural insights into the inhibited states of the Mer receptor tyrosine kinase. J Struct Biol. 2009 Feb;165(2):88-96. Epub 2008 Nov 5. PMID:19028587 doi:10.1016/j.jsb.2008.10.003
- Graham DK, Dawson TL, Mullaney DL, Snodgrass HR, Earp HS. Cloning and mRNA expression analysis of a novel human protooncogene, c-mer. Cell Growth Differ. 1994 Jun;5(6):647-57. PMID:8086340
- Gal A, Li Y, Thompson DA, Weir J, Orth U, Jacobson SG, Apfelstedt-Sylla E, Vollrath D. Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. Nat Genet. 2000 Nov;26(3):270-1. PMID:11062461 doi:10.1038/81555
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Arrowsmith, C H.
- Bochkarev, A.
- Dhe-Paganon, S.
- Edwards, A M.
- Finerty, P J.
- Huang, X.
- SGC, Structural Genomics Consortium.
- Sundstrom, M.
- Walker, J R.
- Weigelt, J.
- Atp-binding
- Disease mutation
- Glycoprotein
- Kinase
- Nucleotide-binding
- Phosphorylation
- Proto-oncogene
- Receptor
- Retinitis pigmentosa
- Sensory transduction
- Sgc
- Structural genomic
- Structural genomics consortium
- Transferase
- Tyrosine-protein kinase
- Vision
