1qlp | pdb_00001qlp

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Template:STRUCTURE 1qlp

File:1qlp.png

2.0 ANGSTROM STRUCTURE OF INTACT ALPHA-1-ANTITRYPSIN: A CANONICAL TEMPLATE FOR ACTIVE SERPINS

Template:ABSTRACT PUBMED 10933492

About this Structure

1qlp is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2psi. Full crystallographic information is available from OCA.

Reference

  1. Elliott PR, Pei XY, Dafforn TR, Lomas DA. Topography of a 2.0 A structure of alpha1-antitrypsin reveals targets for rational drug design to prevent conformational disease. Protein Sci. 2000 Jul;9(7):1274-81. PMID:10933492
  2. Elliott PR, Abrahams JP, Lomas DA. Wild-type alpha 1-antitrypsin is in the canonical inhibitory conformation. J Mol Biol. 1998 Jan 23;275(3):419-25. PMID:9466920 doi:S0022-2836(97)91458-3

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