1h35 | pdb_00001h35

From Proteopedia
Revision as of 21:53, 14 March 2011 by OCA (talk | contribs) (Protected "1h35" [edit=sysop:move=sysop])
Jump to navigationJump to search

Template:STRUCTURE 1h35

File:1h35.png

STRUCTURES OF HUMAN OXIDOSQUALENE CYCLASE INHIBITORS BOUND TO A HOMOLGOUS ENZYME

Template:ABSTRACT PUBMED 12747780

About this Structure

1h35 is a 3 chain structure with sequence from Alicyclobacillus acidocaldarius. Full crystallographic information is available from OCA.

Reference

  1. Lenhart A, Reinert DJ, Aebi JD, Dehmlow H, Morand OH, Schulz GE. Binding structures and potencies of oxidosqualene cyclase inhibitors with the homologous squalene-hopene cyclase. J Med Chem. 2003 May 22;46(11):2083-92. PMID:12747780 doi:https://dx.doi.org/10.1021/jm0211218
  2. Lenhart A, Weihofen WA, Pleschke AE, Schulz GE. Crystal structure of a squalene cyclase in complex with the potential anticholesteremic drug Ro48-8071. Chem Biol. 2002 May;9(5):639-45. PMID:12031670
  3. Wendt KU, Lenhart A, Schulz GE. The structure of the membrane protein squalene-hopene cyclase at 2.0 A resolution. J Mol Biol. 1999 Feb 12;286(1):175-87. PMID:9931258 doi:https://dx.doi.org/10.1006/jmbi.1998.2470
  4. Wendt KU, Poralla K, Schulz GE. Structure and function of a squalene cyclase. Science. 1997 Sep 19;277(5333):1811-5. PMID:9295270
  5. Morand OH, Aebi JD, Dehmlow H, Ji YH, Gains N, Lengsfeld H, Himber J. Ro 48-8.071, a new 2,3-oxidosqualene:lanosterol cyclase inhibitor lowering plasma cholesterol in hamsters, squirrel monkeys, and minipigs: comparison to simvastatin. J Lipid Res. 1997 Feb;38(2):373-90. PMID:9162756

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1h35&oldid=1209397"