2jbj | pdb_00002jbj
From Proteopedia
MEMBRANE-BOUND GLUTAMATE CARBOXYPEPTIDASE II (GCPII) IN COMPLEX WITH 2-PMPA (2-PHOSPHONOMETHYL-PENTANEDIOIC ACID)
Template:ABSTRACT PUBMED 17372356
About this Structure
2jbj is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Mesters JR, Henning K, Hilgenfeld R. Human glutamate carboxypeptidase II inhibition: structures of GCPII in complex with two potent inhibitors, quisqualate and 2-PMPA. Acta Crystallogr D Biol Crystallogr. 2007 Apr;63(Pt 4):508-13. Epub 2007, Mar 16. PMID:17372356 doi:10.1107/S090744490700902X
- Mesters JR, Barinka C, Li W, Tsukamoto T, Majer P, Slusher BS, Konvalinka J, Hilgenfeld R. Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer. EMBO J. 2006 Mar 22;25(6):1375-84. Epub 2006 Feb 9. PMID:16467855
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Glutamate carboxypeptidase II
- Homo sapiens
- Henning, K.
- Hilgenfeld, R.
- Mesters, J R.
- Alternative splicing
- Antigen
- Carboxypeptidase
- Dipeptidase
- Glycoprotein
- Hydrolase
- Membrane
- Metal- binding
- Metal-binding
- Metalloprotease
- Multifunctional enzyme
- Naaladase
- Neurodegenerative disease
- Peptidase
- Polymorphism
- Prostate cancer
- Protease
- Psma
- Signal-anchor
- Transmembrane
- Zinc
