2gnf | pdb_00002gnf

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File:2gnf.png

Template:STRUCTURE 2gnf

Protein kinase A fivefold mutant model of Rho-kinase with Y-27632

Template:ABSTRACT PUBMED 16699172

About this Structure

2gnf is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  1. Bonn S, Herrero S, Breitenlechner CB, Erlbruch A, Lehmann W, Engh RA, Gassel M, Bossemeyer D. Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity. J Biol Chem. 2006 Aug 25;281(34):24818-30. Epub 2006 May 12. PMID:16699172 doi:10.1074/jbc.M512374200
  2. Breitenlechner C, Gassel M, Hidaka H, Kinzel V, Huber R, Engh RA, Bossemeyer D. Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. Structure. 2003 Dec;11(12):1595-607. PMID:14656443

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