2y7x | pdb_00002y7x
From Proteopedia
THE DISCOVERY OF POTENT AND LONG-ACTING ORAL FACTOR XA INHIBITORS WITH TETRAHYDROISOQUINOLINE AND BENZAZEPINE P4 MOTIFS
About this Structure
2y7x is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Watson NS, Adams C, Belton D, Brown D, Burns-Kurtis CL, Chaudry L, Chan C, Convery MA, Davies DE, Exall AM, Harling JD, Irvine S, Irving WR, Kleanthous S, McLay IM, Pateman AJ, Patikis AN, Roethke TJ, Senger S, Stelman GJ, Toomey JR, West RI, Whittaker C, Zhou P, Young RJ. The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1588-92. Epub 2011 Feb 2. PMID:21349711 doi:10.1016/j.bmcl.2011.01.129
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- Coagulation factor Xa
- Homo sapiens
- Adams, C.
- Belton, D.
- Brown, D.
- Burns-Kurtis, C L.
- Chan, C.
- Chaudry, L.
- Convery, M A.
- Davies, D E.
- Exall, A M.
- Harling, J D.
- Irvine, S.
- Irving, W R.
- Kleanthous, S.
- Mclay, I M.
- Pateman, A J.
- Patikis, A N.
- Roethka, T J.
- Senger, S.
- Stelman, G J.
- Toomey, J R.
- Watson, N S.
- West, R I.
- Whittaker, C.
- Young, R J.
- Zhou, P.