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From Proteopedia
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| 1faj, resolution 2.15Å (default scene) | |||||||||||||
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| Activity: | Inorganic diphosphatase, with EC number 3.6.1.1 | ||||||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Soluble inorganic pyrophosphatase is a ubiquitous enzyme that plays an important role in energy metabolism [1]. Energy metabolism is made possible by soluble inorganic pyrophosphatases (PPases) by their hydrolyzing inorganic phosphates into two molecules of orthophosphate [2]. PPases may have had an important role in evolution by aiding in accurate DNA copying during chromosome duplication [1].
Inorganic Pyrophosphatase
Structure
Function
References
- ↑ 1.0 1.1 Kankare J, Neal GS, Salminen T, Glumoff T, Glumhoff T [corrected to Glumoff T, Cooperman BS, Lahti R, Goldman A. The structure of E.coli soluble inorganic pyrophosphatase at 2.7 A resolution. Protein Eng. 1994 Jul;7(7):823-30. PMID:7971944
- ↑ Samygina VR, Popov AN, Rodina EV, Vorobyeva NN, Lamzin VS, Polyakov KM, Kurilova SA, Nazarova TI, Avaeva SM. The structures of Escherichia coli inorganic pyrophosphatase complexed with Ca(2+) or CaPP(i) at atomic resolution and their mechanistic implications. J Mol Biol. 2001 Nov 30;314(3):633-45. PMID:11846572 doi:10.1006/jmbi.2001.5149
