Sandbox Reserved 324

This Sandbox is Reserved from January 10, 2010, through April 10, 2011 for use in BCMB 307-Proteins course taught by Andrea Gorrell at the University of Northern British Columbia, Prince George, BC, Canada.

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Introduction

eIF2 is one of the many initiating factors needed for eukaryotic initiation recently discovered.

spinqualitylabelsall models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D load='1q8k' size='350' frame='false' scene=
1q8k, 15 NMR models (default scene)
Gene:	EIF2S1 OR EIF2A (Homo sapiens)
Structural annotation: Resources: CATH : 1Q8Ka02, 1Q8Ka01, 1Q8Ka03 InterPro : Ipr011488, Ipr003029, Ipr012340 Pfam : PF00575, PF07541 SCOP : d1q8ka1, d1q8ka2 UniProt : P05198
Functional annotation: Cellular component: cytoplasm polysome nucleus eukaryotic translation initiation factor 2 complex eukaryotic translation initiation factor 2B complex Biological process: translation regulation of translational initiation in response to stress regulation of translation Molecular function: RNA binding protein binding translation initiation factor activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml