2xae

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Template:STRUCTURE 2xae

File:2xae.jpg

CRYSTAL STRUCTURE OF HUMAN KINESIN EG5 IN COMPLEX WITH (R)-2-AMINO-3-((S)-2-METHYL-1,1-DIPHENYLBUTYLTHIO)PROPANOIC ACID

Template:ABSTRACT PUBMED 21344920

About this Structure

2xae is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Kaan HY, Weiss J, Menger D, Ulaganathan V, Tkocz K, Laggner C, Popowycz F, Joseph B, Kozielski F. Structure-Activity Relationship and Multidrug Resistance Study of New S-trityl-l-Cysteine Derivatives As Inhibitors of Eg5. J Med Chem. 2011 Mar 24;54(6):1576-1586. Epub 2011 Feb 23. PMID:21344920 doi:10.1021/jm100991m

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