3rhk | pdb_00003rhk

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Template:STRUCTURE 3rhk

File:3rhk.jpg

Crystal structure of the catalytic domain of c-Met kinase in complex with ARQ 197

Template:ABSTRACT PUBMED 21454604

About this Structure

3rhk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Eathiraj S, Palma R, Volckova E, Hirschi M, France DS, Ashwell MA, Chan TC. Discovery of a novel mode of protein kinase inhibition characterized by the mechanism of inhibition of human mesenchymal-epithelial transition factor (c-MET) autophosphorylation by ARQ 197. J Biol Chem. 2011 Mar 24. PMID:21454604 doi:10.1074/jbc.M110.213801

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