3rhx | pdb_00003rhx
From Proteopedia
Crystal structure of the catalytic domain of FGFR1 kinase in complex with ARQ 069
About this Structure
3rhx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Eathiraj S, Palma R, Hirschi M, Volckova E, Nakuci E, Castro J, Chen CR, Chan TC, France DS, Ashwell MA. A novel mode of protein kinase inhibition exploiting hydrophobic motifs of auto-inhibited kinases: discovery of ATP independent inhibitors of fibroblast growth factor receptor (FGFR). J Biol Chem. 2011 Mar 24. PMID:21454610 doi:10.1074/jbc.M110.213736
