3pz4 | pdb_00003pz4

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Template:STRUCTURE 3pz4

File:3pz4.jpg

Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10) in complex with BMS3 and lipid substrate FPP

About this Structure

3pz4 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Bon RS, Guo Z, Stigter EA, Wetzel S, Menninger S, Wolf A, Choidas A, Alexandrov K, Blankenfeldt W, Goody RS, Waldmann H. Structure-Guided Development of Selective RabGGTase Inhibitors. Angew Chem Int Ed Engl. 2011 May 16;50(21):4957-61. doi:, 10.1002/anie.201101210. Epub 2011 Apr 21. PMID:21520375 doi:10.1002/anie.201101210

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