3qix | pdb_00003qix

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File:3qix.png

Template:STRUCTURE 3qix

Crystal Structure of BoNT/A LC with Zinc bound

Template:ABSTRACT PUBMED 21434688

About this Structure

3qix is a 2 chain structure with sequence from Clostridium botulinum. Full crystallographic information is available from OCA.

Reference

  1. Thompson AA, Jiao GS, Kim S, Thai A, Cregar-Hernandez L, Margosiak SA, Johnson AT, Han GW, O'Malley S, Stevens RC. Structural Characterization of Three Novel Hydroxamate-based Zinc Chelating Inhibitors of the C. botulinum Serotype A Neurotoxin Light Chain Metalloprotease Reveals a Compact Binding Site Resulting from 60/70 Loop Flexibility. Biochemistry. 2011 Mar 24. PMID:21434688 doi:10.1021/bi2001483

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