2djw | pdb_00002djw
Crystal structure of TTHA0845 from Thermus thermophilus HB8
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Overview
The stand-alone RAM (regulation of amino-acid metabolism) domain protein, SraA from Thermus thermophilus HB8 (TTHA0845) was crystallized in the, presence of zinc ions. The X-ray crystal structure was determined using a, multiple-wavelength anomalous dispersion technique and was refined at 2.4, A resolution to a final R factor of 25.0%. The monomeric structure is a, betaalphabetabetaalphabeta fold and it dimerizes mainly through, interactions between the antiparallel beta-sheets. Furthermore, five SraA, dimers form a ring with external and internal diameters of 70 and 20 A, respectively. This decameric structure is unique compared with the, octameric and dodecameric structures found for other stand-alone, RAM-domain proteins and the C-terminal RAM domains of Lrp/AsnC-family, proteins.
About this Structure
2DJW is a Single protein structure of sequence from Thermus thermophilus with ZN as ligand. Full crystallographic information is available from OCA.
Reference
Structure of the stand-alone RAM-domain protein from Thermus thermophilus HB8., Nakano N, Okazaki N, Satoh S, Takio K, Kuramitsu S, Shinkai A, Yokoyama S, Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Sep 1;62(Pt, 9):855-60. Epub 2006 Aug 26. PMID:16946463
Page seeded by OCA on Tue Jan 29 19:04:22 2008
Proteopedia Page Contributors and Editors (what is this?)
- Pages with broken file links
- Single protein
- Thermus thermophilus
- Nakano, N.
- Okazaki, N.
- RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.
- Shinkai, A.
- Yokoyama, S.
- ZN
- National project on protein structural and functional analyses
- Nppsfa
- Riken structural genomics/proteomics initiative
- Rsgi
- Structural genomics
- Thermus thermophilus hb8
